Association of glutathione S-transferase 1 (GSTP1) polymorphisms with Breast Cancer susceptibility

Hereditary and environmental variables have a role in the development of breast cancer. This study aimed to examine links between genetic Variations GSTP1 gene Predisposition cancer an Iraqi population. The research included 40 female patients 20 healthy volunteers. GSTP1-1695 A/G polymorphisms were investigated using polymerase chain reaction Real-time (RT-PCR). results showed frequency wild GG genotypes was significantly (P<0.01) higher women comparison with Breast (GG, 80% vs. 32.5%, respectively; furthermore, heterozygous AG 42.5% 20%, respectively at (P<0.01). While mutant AA genotype (25%) patient appeared compared (0.0%). Finally, we discovered connection chance developing population sample. Keywords: glutathione S-transferase1, cancer, polymorphism.